过敏性休克是外界某些抗原性物质进入致敏机体后,通过免疫机制在短时间内触发的一种严重的全身性过敏性反应,多突然发生且极为严重,若不及时处理可危及生命。本文报道1例因双乳肿物,于全麻下行双乳肿物切除术,在麻醉诱导期出现过敏性休克,经过抢救后复苏成功并完成手术,通过回顾以往文献,总结抢救经验及休克纠正后并发症的处理提供参考。Anaphylactic shock is a severe anaphylactic reaction triggered by the immune mechanism in a short period of time after some antigenic substances from the outside world enter the sensitized body, which occurs suddenly and is extremely serious, and can be life-threatening if not treated in time. This article reports that a case of double breast mass resection underwent general anesthesia due to double breast mass, and anaphylactic shock occurred during the anesthesia induction period, and the recovery was successful and the operation was completed after rescue. Summarize the experience of shock rescue and provide reference for the management of complications after shock correction by reviewing previous literature.
目的:研究绝经后女性乳腺癌的身体质量指数(body mass index,BMI)与临床病理特征的相关性。方法:对我医院2018年4月-2019年4月的212例乳腺癌病例进行回顾性研究,收集患者的各项临床数据,根据体质量指数情况,将入选患者分成了163例的正常组(BMI<24 kg/m^(2))和49例的肥胖组(24 kg/m^(2))。对比两组患者的各项基础的临床病理学特征。结果:(1)肥胖组内的乳腺癌患者,年龄相比于正常组明显更高,(P均<0.05);但在患侧构成比方面,两组对比无统计学意义,(P>0.05);(2)在新辅助化疗占比,病理分期以及肿瘤浸润灶方面的对比中,肥胖组的数据显著更大,两者之间的差别显著,有统计学意义,(P<0.05)。(3)在总淋巴清扫数、腋窝淋巴结分期及肿瘤组织学分级方面,两组相比较无显著性差异(P>0.05)。结论:与BMI正常的绝经后乳腺癌患者相比较,BMI高者在分期、化疗比例更高,并且肿瘤的浸润灶更大,猜测可能是因为肥胖群体的脂肪厚度与乳房体积更大相关,所以在疾病的早期很难发现病变。
