针灸作为中医的基石,在西方医学中因其通过神经内分泌调节治疗精神障碍的潜力而得到认可。本综述探讨了神经内分泌系统在调节情绪、压力和心理健康方面的作用,重点研究了下丘脑–垂体–肾上腺轴、下丘脑–垂体–甲状腺轴、下丘脑–垂体–性腺轴、神经递质(血清素、多巴胺、γ-氨基丁酸)和皮质醇等关键组成部分。讨论了针灸对这些元素的影响,强调了其对神经内分泌轴和神经递质系统的双向调节作用。证据表明,针灸在治疗焦虑、抑郁、失眠和创伤后应激障碍方面具有疗效,展示了其作为心理健康护理辅助疗法的潜力。尽管需要进一步的高质量研究,但当前的证据支持针灸在治疗精神障碍中的作用。本综述强调了针灸通过神经内分泌调节的治疗潜力,并倡导继续研究和临床应用,以扩大精神障碍的治疗选择。Acupuncture, a cornerstone of Traditional Chinese Medicine, has gained recognition in Western medicine for its potential to treat mental disorders through neuroendocrine modulation. This review explores the neuroendocrine system’s role in regulating mood, stress, and mental health, focusing on key components such as the hypothalamic-pituitary-adrenal axis, hypothalamic-pituitary-thyroid axis, hypothalamic-pituitary-gonadal axis, neurotransmitters (serotonin, dopamine, gamma-aminobutyric acid), and cortisol. The effects of acupuncture on these elements are discussed, highlighting its bidirectional modulation of neuroendocrine axes and neurotransmitter systems. Evidence suggests acupuncture’s efficacy in treating anxiety, depression, insomnia, and post-traumatic stress disorder, demonstrating its potential as an adjunctive therapy for mental health care. While further high-quality research is necessary, current evidence supports acupuncture’s role in mental disorders treatment. This review underscores acupuncture’s therapeutic potential through neuroendocrine regulation and ad