The objective of this study is to investigate a high performance and lower cost compact gamma camera module for a multi-head small animal SPECT system. A compact camera module was developed using a thin Lutetium Oxyorthosilicate (LSO) scintillation crystal slice coupled to a Hamamatsu H8500 position sensitive photomultiplier tube (PSPMT). A two-stage charge division readout board based on a novel subtractive resistive readout with a truncated center-of-gravity (TCOG) positioning method was developed for the camera. The performance of the camera was evaluated using a flood 99roTe source with a four-quadrant bar-mask phantom. The preliminary experimental results show that the image shrinkage problem associated with the conventional resistive readout can be effectively overcome by the novel subtractive resistive readout with an appropriate fraction subtraction factor. The response output area (ROA) of the camera shown in the flood image was improved up to 34%, and an intrinsic spatial resolution better than 2 mm of detector was achieved. In conclusion, the utilization of a continuous scintillation crystal and a flat-panel PSPMT equipped with a novel subtractive resistive readout is a feasible approach for developing a high performance and lower cost compact gamma camera.
This study was aimed at developing an efficient simulation technique with an ordinary PC.The work involved derivation of mathematical operators,analytic phantom generations,and effective analytical projectors developing for cone-beam CT and pinhole SPECT imaging.The computer simulations based on the analytical projectors were developed by ray-tracing method for cone-beam CT and voxel-driven method for pinhole SPECT of degrading blurring.The 3D Shepp-Logan,Jaszczak and Defrise phantoms were used for simulation evaluations and image reconstructions.The reconstructed phantom images were of good accuracy with the phantoms.The results showed that the analytical simulation technique is an efficient tool for studying cone-beam CT and pinhole SPECT imaging.
This work aims at developing compact readout electronics for a compact imaging detector module with silicon photomultiplier (SPM) array. The detector module consists of a LYSO crystal array coupling with a SensL’s 4×4 SPM array. A compact multiplexed readout based on a discretized positioning circuit (DPC) was developed to reduce the readout channels from 16 to 4 outputs. Different LYSO crystal arrays of 4×4, 8×8 and 12×12 with pixel sizes of 3.2, 1.6 and 1.0 mm respectively, have been tested with the compact readout board using a 137 Cs source. The initial results show that the compact imaging detector module with the compact multiplexed readout could clearly resolve 1 mm×1 mm×10 mm LYSO scintillation crystal array except those at the edges. The detector’s intrinsic spatial resolution up to 1 mm can be achieved with the 3 mm×3 mm size SPMArray4 through light sharing and compact multiplexed readout. Our results indicate that this detector module is feasible for the development of high-resolution compact PET.